2-OCA has a superior cosmetic outcome at 1 year

The lower visual rating represented a superior cosmetic outcome at 1 year with the octyl-2-cyanoacrylate as compared with sutures. This difference is statistically significant at p = 0.03. Additionally, patient satisfaction was very high in the group treated with octyl-2-cyanoacrylate.


2-OCA has a shorter operation time than suture

 


2-OCA has a higher wound-closure-bursting strengths (WBS) than butyl-cyanoacrylate, whose WBS is greater than that of surgical tape

 


2-OCA has less pain than suture

 


The comparison between 2-OCA and nBCA:

2-Octyl cyanoacrylate (2-OCA) and butyl-cyanoacrylate (NBCA) are the only two approved cyanoacrylate tissue adhesives on the market. Butyl-2-cyanoacrylate is effective in closing superficial lacerations under low tension. However, it has several limitations:

• Less wound-closure-breaking strength in wound-closures repaired with butyl-2-cyanoacrylate

• nBCA is more brittle than 2-OCA and is subject to fracturing when used in skin creases or long incisions

This restricts the use of adhesives to areas of low tension, thus limiting their use for incision repair. 2-octyl cyanoacrylate was formulated to correct some of the deficiencies of the nBCA. It has the following advantages:

• 2-OCA has lower concentrations of the degradation by-products in surrounding tissues, resulting in less inflammation.

• 2-OCA is more pliable and flexes with the skin and remains inherent for longer periods of time. This stronger flexible bond may allow its use on longer incisions.

• 2-OCA was approved by the US FDA in January 2001 for use as a barrier against common bacterial microbes including certain staphylococci.

• 2-OCA has been used widely with good cosmetic outcomes for various plastic surgical procedures (eg, upper lid blepharoplasty, facial skin closure, scalp wound-closure closure).

Other References

1. The use of 2-OCA to prevention of postoperative pancreatic fistula after pancreaticoduodenectomy.

2. The use of 2-OCA for repairing facial wound-closures following Mohs micrographic surgery

3. The use of 2-OCA for circumcision

4. The use of 2-OCA in the management of lacerations

5. The use of 2-OCA for the closure of head and neck incisions

6. The use of 2-OCA for the closure of pediatric hernia incisions

7. The use of 2-OCA for the closure of Laparoscopic Cholecystectomy incisions

A Prospective Randomized Trial Comparing 2-Octyl Cyanoacrylate to Conventional Suturing in Closure of Laparoscopic Cholecystectomy Incisions

Tissue Aid